How is spontaneous abortion to return a responsibility?
summary
Spontaneous abortion refers to the spontaneous termination of pregnancy before 28 weeks, the fetal weight < 1000g. There are many controversies about the term of abortion. In some countries, the term of abortion is set at 25 weeks, or even 20 weeks, because in developed countries, newborns with gestational age over 20 weeks and weight of 600-700g have a chance to survive due to adequate treatment. So how is spontaneous abortion going on?
How is spontaneous abortion to return a responsibility?
Some chronic reproductive tract infections are considered to be one of the causes of early abortion. The pathogen that can cause recurrent abortion is often persistent in the reproductive tract, and the mother rarely produces symptoms, and this pathogen can directly or indirectly lead to embryo death. Retrograde infection of reproductive tract usually occurs before 12 weeks of pregnancy. After this period, the placenta and decidua fuse to form a mechanical barrier. With the progress of pregnancy, the anti infectivity of amniotic fluid gradually increases, and the chance of infection decreases.
The abortion caused by immune factors, especially recurrent abortion and habitual abortion, can be divided into two types, namely autoimmune type and alloimmune type. Autoimmune type usually can detect various autoantibodies from patients, mainly antiphospholipid antibodies. Alloimmune patients were screened for common causes, so it is also called unexplained habitual abortion; These are mainly related to the poor physiological protective immune response during pregnancy, the lack of immunosuppressive factors or blocking factors, and eventually the embryo suffered from immune damage, leading to abortion.
Chromosome abnormalities include chromosome number abnormalities, such as monosomy, trisomy and polyploidy; Structural abnormalities, such as breakage, deletion and translocation, can lead to abortion. It was found that 60% of spontaneous abortion had abnormal karyotype. The abnormal karyotype is accompanied by a structural abnormality of fetus or placenta. The normal karyotype of abortion fetus is more normal.
matters needing attention
Before pregnancy, go to the hospital for physical examination, especially those who have a history of abortion in the past, they should have a comprehensive examination. If they find some diseases, they should be treated first, and then get pregnant after the disease is cured. Some patients with uterine malformation can be operated to correct the deformity; Rubella virus, Toxoplasma gondii, herpes simplex infection, should be treated first, until the examination turned negative before pregnancy; If you have luteal insufficiency, hyperthyroidism, severe anemia, diabetes and other diseases, you should control the disease before you plan to get pregnant; Patients with cervical laceration should be treated with cervical canal repair; In order to prevent abortion, cervical cerclage should be performed at 14-16 weeks of pregnancy.
