Pantoprazole sodium

summary

Due to the fast pace of modern life, irregular diet, unhealthy diet, like to eat some fried hot and sour food, these are the important factors leading to the high incidence of people's stomach disease. If early stomach disease is not treated in time, it will aggravate the disease and easily lead to other diseases. Therefore, for patients with mild stomach disease, we should also pay attention to the treatment of stomach disease. Pantoprazole sodium is commonly used in the treatment of esophagitis and gastric ulcer. What should be paid attention to when pantoprazole sodium is used? Next, the content of this aspect is introduced in detail.

Pantoprazole sodium

The first treatment includes duodenal ulcer, gastric ulcer, reflux esophagitis and Zhuo AI syndrome, especially for ulcer with bleeding, vomiting or inability to eat, as well as refractory ulcer and acute pancreatitis. It can also be used to prevent stress ulcer caused by major operation or severe trauma.

The second is intravenous drip. Before use, inject 3ml 0.9% sodium chloride injection into lyophilized powder vial, and add the dissolved solution into 100-250ml 0.9% sodium chloride injection for intravenous drip. Intravenous drip should be completed within 15-60 minutes. This product must be used up within 4 hours after dissolution and dilution. It is forbidden to dissolve and dilute with other solvents or other drugs.

Thirdly, pantoprazole sodium can be metabolized through the first system of cytochrome P450 enzymes in hepatocytes, and also through the second system. When combined with other drugs metabolized through P450 enzyme system, pantoprazole sodium can be metabolized through the second enzyme system, so it is not easy to have the competitive effect of drug metabolizing enzyme system and reduce the drug interaction in vivo. It has no mutagenic, carcinogenic and teratogenic effects.

matters needing attention

It can inhibit gastric acid secretion for a long time, so it is not suitable to take other antacids or antacids at the same time. In order to prevent excessive acid suppression, gastric cancer should be excluded before using this product in the treatment of gastric ulcer, so as not to delay the diagnosis and treatment. There is no need to adjust the dosage for patients with renal function impairment, and the dosage should be reduced for patients with liver function impairment.