How does protein allergy return a responsibility?

summary

Egg allergens mainly exist in the egg white, you can eat some light things, egg white contains 23 different proteins and some secondary proteins. So what's the matter with protein allergy? I hope this problem can help some people.

How does protein allergy return a responsibility?

First, it is found that there are four kinds of protein components in egg white, which can combine with human serum and cause allergic reaction. They are generally recognized as the main allergens of eggs. They are ovomucoid protein, ovalbumin, ovotransferrin and lysozyme.

Second: egg allergy is an immune disease, its pathogenesis is more complex, the most common is immunoglobulin E (IGE) - mediated rapid type hypersensitivity, the reaction mechanism is type I hypersensitivity, including sensitization and sensitization two stages.

Third, when a certain amount of allergens induce susceptible individuals to produce enough IgE, IgE distributes throughout the body through blood circulation, and binds to specific receptors on the surface of mast cells and basophils, so that the body is in a sensitized state. When the human body comes into contact with food containing the same or similar allergen components again, the allergen molecules specifically recognize the IgE on the surface of the sensitized cell membrane, induce the cell particles to release inflammatory mediators and trigger food allergy.

matters needing attention

It has been reported that it seems feasible to gradually increase the dosage of allergic food to obtain oral tolerance. With the increase of daily egg intake in 90% of allergic patients, the serum ovalbumin specific IgE level was significantly decreased by skin prick test, but in the following 1-6 months of observation, it was found that the release of cytokines was increased, so a small amount of allergic food may induce tolerance, but it can not be called desensitization.