What are the symptoms of signet ring cell carcinoma?

summary

Signet ring cell carcinoma of the stomach is named after the appearance of a large amount of mucus in the cytoplasm of cancer cells, pushing the nucleus to one side and looking like a ring. Signet ring cell carcinoma of the stomach accounts for about 9.9% of gastric cancer. It is a tumor with rapid progression and poor prognosis. It occurs in young women. Most experts believe that the occurrence of the disease may be related to the vigorous metabolism of estrogen in young women. What are the symptoms of signet ring cell carcinoma? Let's talk about it

What are the symptoms of signet ring cell carcinoma?

In the early stage, most patients had no obvious symptoms, and a few had nausea, vomiting or upper gastrointestinal symptoms similar to ulcer disease. Pain and weight loss are the most common clinical symptoms in advanced patients. Patients often have more definite upper gastrointestinal symptoms, such as abdominal discomfort, fullness after eating, and upper abdominal pain aggravating with the progress of the disease,

Loss of appetite and fatigue. According to the location of the tumor, there are also special manifestations. Cancer of cardia and fundus of stomach may have retrosternal pain and progressive dysphagia; Patients with lesions near the pylorus had pylorus obstruction; After the tumor destroys the blood vessel, may have hematemesis, black stool and so on digestive tract hemorrhage symptom.

Persistent abdominal pain often indicates tumor expansion beyond the gastric wall, such as supraclavicular lymphadenopathy, ascites, jaundice, abdominal mass, anterior rectal fossa and mass. Late stage patients often appear anemia, emaciation, malnutrition and even cachexia.

matters needing attention

Palliative surgery can not remove the primary focus, in order to reduce the symptoms caused by obstruction, perforation, bleeding and other complications, such as gastrojejunostomy, jejunostomy, perforation repair, palliative gastrectomy, etc.