Early symptoms of neuroendocrine carcinoma?

summary

Neuroendocrine tumors are rare, accounting for less than 1% of all malignant tumors. Most of them occur in stomach, intestine and pancreas. Carcinoid is the most common tumor in this kind of tumor, with an incidence of about 2.5/100000, accounting for 50% of all gastrointestinal and pancreatic neuroendocrine tumors. According to the origin, carcinoid can be divided into foregut (lung, bronchus and upper gastrointestinal tract up to jejunum), midgut (ileum and appendix) and hindgut (rectum and rectum). This kind of tumor can occur in the whole neuroendocrine system, but the most common site of involvement is the pancreas. According to whether the substances secreted by tumors cause typical clinical symptoms, neuroendocrine tumors can be divided into two categories: functional and nonfunctional. Now let's talk about the early symptoms of neuroendocrine cancer.

Early symptoms of neuroendocrine carcinoma?

First, carcinoid syndrome: sudden or persistent skin flushing of head, face and trunk, which can be induced by alcohol, strenuous activities, mental stress or eating food containing 3-hydroxyaniline, such as chocolate and banana; Mild or moderate diarrhea, diarrhea and skin flushing may not exist at the same time, may be associated with increased intestinal peristalsis, may be accompanied by abdominal pain; Carcinoid related heart diseases, such as pulmonary artery stenosis, tricuspid regurgitation, etc; Other symptoms such as skin telangiectasia, pellagra, occasionally dermatitis, dementia and diarrhea triad.

Second: gastrinoma is often manifested as Zollinger Ellison syndrome, abdominal pain, diarrhea, intermittent diarrhea, dysentery, and recurrent peptic ulcer.

Third: glucagonoma is often accompanied by excessive glucagon secretion. The typical manifestation is necrotic migratory erythema with anemia and thrombocytopenia. About half of the patients may have moderate diabetes, and may also have painful red tongue, dry lip, venous thrombosis, intestinal obstruction and constipation.

matters needing attention

It is suitable to eat fresh vegetables and fruits, beans, lettuce, water chestnut, meat, dairy products, etc. Eat less or no sausage, ham and salted products. In addition to increasing the intake of the above foods, we should also pay attention to keep away from those tumorigenic diets. In the daily diet, we should avoid eating withered, yellow and spotted fruits, vegetables, moldy and deteriorated peanuts, grains and beans; Do not eat salted fish, meat, pickles, etc; In addition, cancer patients should eat less fried, fried, fat and other greasy, indigestible food.