Is antinuclear antibody positive person much?

summary

In fact, there is a system in our body called the immune system. This system specially produces some cells or antibodies to fight against the bacteria or viruses that invade our body and prevent the body from being infected by these microorganisms. Is antinuclear antibody positive person much? Let's talk about it

Is antinuclear antibody positive person much?

Many patients think that antinuclear antibody is a single antibody, this view is wrong. At present, the body substance targeted by antibody is called target antigen. In the past, Ana was regarded as a group of autoantibodies that take various nuclear related components in human cells as target antigen. Recently, it is believed that the distribution of target antigen is not limited to the nucleus, but also includes some nuclear proteins and nucleic acids in the cytoplasm.

The body produces different antinuclear antibodies against different nuclear antigens. There are five kinds of antibodies in the body, which are called IgG, IgM, IgA, IgD and IgE. ANA is mainly IgG, but there are also IgM, IgA and IgD, but these antibodies do not target a certain organ or a specific species of animals.

ANA exists in serum, pleural fluid, synovial fluid and urine. At present, Ana includes five categories, each of which is further divided into many subclasses due to different antigenic characteristics, so it is called antinuclear antibody spectrum. Different combinations of ANA appear in different autoimmune diseases, which become the characteristic antibody spectrum of various diseases. The detection of antinuclear antibodies in different combinations is of great significance for the diagnosis of diseases.

matters needing attention

As antinuclear antibodies are of great importance to the human body, it is necessary to have regular physical examination, so as to avoid the occurrence of diseases. The initial screening positive of antinuclear antibody does not necessarily mean that the patient has lupus, but needs to pass the detection of antinuclear antibody spectrum, as well as comprehensive judgment with other conditions of the body.