Symptoms of duodenal cancer?

summary

Benign tumor of duodenum is less common than malignant tumor. The ratio of benign to malignant is 1 ∶ 2.6-1 ∶ 6.8. Although duodenal benign tumors are benign, some of them have a high tendency of malignant transformation. Some of them are between benign and malignant, and even are difficult to differentiate under microscope. In particular, the location of tumor growth is often closely related to the biliary and pancreatic drainage system, the location is fixed, and the intestinal cavity of duodenum is relatively narrow, so it often causes various symptoms, even serious complications and life-threatening. Because of the special location of duodenum, the surgical treatment of these tumors is very difficult.

Symptoms of duodenal cancer?

Functional dyspepsia is characterized by epigastric pain or discomfort with fullness, acid regurgitation, belching and other manifestations. Physical examination can be completely normal or only mild epigastric tenderness. Gastroscopy and X-ray examination can be used to identify functional dyspepsia.

It is difficult to distinguish benign ulcer from malignant ulcer in clinic. Sometimes cancerous ulcer can heal temporarily after treatment, so it is easy to be misdiagnosed as benign ulcer. Generally speaking, when barium meal examination, if it is found that the niche is located in the contour of gastric cavity, the mucosa around the niche is rigid and rigid, and the mucosal folds gathered to the ulcer are interrupted, it is the characteristics of malignant ulcer.

Also known as Zollinger Ellison syndrome, it is a non pancreatic disease β The tumor is caused by secreting a large amount of gastrin. It is characterized by abnormal increase of serum gastrin, increased gastric acid secretion, multiple upper gastrointestinal ulcers and refractory ulcers with diarrhea. Compared with common peptic ulcer, gastrinoma caused by ulcer is multiple, location is not typical (such as retrobulbar, jejunum), and is difficult to cure, complications are common. The detection of gastric acid secretion and serum gastrin is helpful for the differential diagnosis of the two diseases. B-ultrasound, CT and MRI examination can help the diagnosis of the disease if there are small tumors in the pancreas or other tissues.

matters needing attention

The symptoms of duodenal ancylostomiasis may be similar to duodenal ulcer, but gastroscopy is helpful for diagnosis if the body or bleeding point of ancylostomiasis is found in the descending part of duodenum, or the eggs of ancylostomiasis are found in fecal examination.