Fibromatosis with multiple hyaline degeneration?

summary

According to the different age and location of onset, it mainly includes juvenile fibromatosis, cervical fibromatosis, infantile fibromatosis, infantile myofibromatosis, adipofibromatosis and so on. The age of onset is mostly 30-50 years old, and children and adolescents are not uncommon. Fibromatosis with multiple hyaline degeneration? Let's talk about it

Fibromatosis with multiple hyaline degeneration?

Multiple hyaline degeneration fibromatosis is a kind of familial multiple fibromatosis with special morphology, involving children. It has no manifestation at birth and may be caused by congenital metabolic abnormalities. Lipofibromatosis is a subtype of infantile fibromatosis, local recurrence is common.

Infantile finger (toe) fibromatosis is a kind of fibromatosis that usually occurs only in childhood. Its typical location is in the end of the finger (toe) outside the side, can also occur outside the finger (toe) parts, such as the oral cavity and breast. The disease is often multiple, and more at birth or within the age of 2 years.

Infantile myofibromatosis is a single or multiple nodular lesion that occurs in skin, soft tissue or bone. It can be limited to the above-mentioned parts, and may also be accompanied by visceral involvement. Most of the cases occur before 2 years old, and about 60% of them are congenital. The disease can also be seen in adults, the single cases are more common in men, while the multiple cases are more common in women. Familial disease is known and evidence of autosomal dominant inheritance has been found.

matters needing attention

Radiotherapy may be effective for local control of the disease and can be used after conservative surgery. In some cases, endocrine therapy has been successful, such as tamoxifen. Younger patients and larger tumors have higher recurrence rates.