What symptom does melancholia have, take what medicine

summary

This may be the most concern of many patients with depression. According to the severity of the disease, the performance and the quality of patients, there will be different choices in the drug treatment of depression. Here are some knowledge about antidepressant drugs to help you better understand antidepressant drugs.

What symptom does melancholia have, take what medicine

First: tricyclic antidepressants: they are commonly used antidepressants, mainly including imipramine, amitriptyline, doxepin, clomipramine, norimipramine, etc. Its pharmacological action is related to blocking the reuptake of norepinephrine and 5-hydroxytryptamine in the brain. It can inhibit the reuptake of norepinephrine and 5-hydroxytryptamine by presynaptic membrane of nerve endings, so as to increase the concentration of neurotransmitters in receptor site and play an antidepressant role.

Second: bicyclic and tetracyclic antidepressants: represented by maprotiline, their pharmacological effects are similar to tricyclic antidepressants.

Third: monoamine oxidase inhibitor: it can be divided into reversible and non reversible. The reversible is represented by moclobemide, and the non reversible is represented by phenethylhydrazine. Because of the high toxicity of this kind of drug, it has been rarely used. Its pharmacological action is to inhibit monoamine oxidase, reduce the degradation of norepinephrine, 5-hydroxytryptamine and dopamine, increase the content of catecholamine in brain and play an antidepressant role.

matters needing attention

Patients with liver and kidney dysfunction should reduce the dosage according to their own discretion. Patients with epilepsy, hematopathy, pregnant and lactating women should use it with caution. Overdose is safe. The dosage should be reduced gradually within 1-2 weeks.