Symptoms of Wright's syndrome

summary

Wright's syndrome (RS) is a serious adverse drug reaction with high mortality. This disease is a rare disease in the recovery process of children with viral infection (such as influenza, cold or chickenpox). Taking salicylic acid drugs (such as aspirin) is an important cause. What are the symptoms of Wright's syndrome? Let's talk about it

Symptoms of Wright's syndrome

The symptoms of the disease may appear during the period of viral disease, but more often after a week or two. Initially, the child usually vomits incessantly. Other early symptoms include diarrhea, fatigue, and mental distress.

As the disease worsens and affects the brain, the child may become restless, hyperactive, delirious, convulsive or epileptic, or even comatose. Most of the white blood cell count increased significantly, mainly neutrophils.

Blood ammonia, plasma free fatty acid and short chain fatty acid increased. Most of the children's blood glucose decreased, and a small number of children's blood glucose was normal. In addition to the headache caused by elevated pressure, the number of cells and proteins were mostly within the normal range.

matters needing attention

The key point is to correct metabolic disorder, control brain edema, reduce intracranial pressure and control convulsion. It is mainly aimed at the two basic pathophysiological changes of the disease, namely brain edema and liver failure. The patients with severe or above encephalopathy must be monitored by cardiopulmonary and intracranial pressure to find out the abnormality in time. As the disease changes rapidly, often from mild to severe suddenly, so the disease should also be closely observed.