What is the false positive reaction of syphilis?

summary

The false positive of syphilis serum reaction is that after infection with syphilis, two kinds of antibodies will be produced in the human body. One is the antibody directly against Treponema pallidum, the other is the antibody against lipid. What is the false positive reaction of syphilis? Next, I'd like to share my views with you.

What is the false positive reaction of syphilis?

In clinical practice, the diseases leading to false-positive syphilis include genital herpes, diabetes, AIDS, hepatitis C, systemic lupus erythematosus, liver cirrhosis and so on. At present, the detection methods of syphilis antibody include RPR, trust, TPPA, etc. if the results of syphilis screening test of patients show positive, it is generally non-specific antibody, but the next step is to see whether the specific antibody is positive.

If the results of syphilis test show that non-specific antibody is positive: syphilis specific antibody is positive, then the patient's serum is problematic, can be diagnosed as syphilis, need treatment. If the test serum showed that syphilis non-specific antibody was positive, but syphilis specific antibody was negative; So it's a false positive.

If there is false positive in syphilis serum test, as long as there is no unclean sexual contact in daily life, at the same time, it should be excluded that the spouse or parents are syphilis patients, have a suspicious history of blood transfusion, stay in unclean hotels, take a sauna and other non sexual contact routes of transmission, and so on. Even if the syphilis test results show that it is positive, it is not enough to be afraid.

matters needing attention

Although Syphilis Serological Examination is very necessary, it is also an important basis for the diagnosis of syphilis, but it is not the only basis for the diagnosis of syphilis. The best way to diagnose syphilis is to have a detailed understanding of the life history and family history, and then pass a detailed physical examination. Only after comprehensive analysis by experienced doctors can we make a prudent judgment, In order to avoid misdiagnosis caused by false positive results of syphilis test.