What reason is leucocyte total number on the low side

summary

It seems that the low total number of white blood cells is not a particularly strange disease. We are not unfamiliar with white blood cells. The old name of white blood cells is white blood cells. White blood cells are a kind of cells in the blood. According to whether there are special granules in the cytoplasm of leukocytes, they can be divided into granulocyte and agranulocyte. The former is often referred to as granulocyte, which can be divided into neutrophils, basophils and eosinophils according to the staining characteristics of its special granules. White blood cells are also commonly referred to as immune cells. The role of white blood cells on the human body is very large, if the body will reduce white blood cells to bring harm to the human body, then what is the cause of white blood cells to reduce it. Let's take a look at the following

What reason is leucocyte total number on the low side

First: drug-induced damage, anti-tumor drugs and immunosuppressants can directly kill the proliferation of cell populations, drugs inhibit or interfere with the synthesis of granulocyte nucleic acid, affect cell metabolism, hinder cell division. The direct toxicity of drugs leads to granulocytopenia, or many kinds of drugs have direct cytotoxicity or immune mechanism.

Second: or due to immune factors, because human autoimmune granulocytopenia is due to the role of autoantibodies, T lymphocytes or natural killer cells in the different stages of granulocyte differentiation, resulting in bone marrow injury and granulopoiesis disorder. Common in rheumatism and autoimmune diseases.

Third: cell maturation disorder ineffective hematopoiesis, such as folic acid and vitamin B12 deficiency, affect DNA synthesis, bone marrow hematopoiesis is active, but cell maturation stagnation and destruction in the bone marrow. Some congenital agranulocytosis, acute non lymphocytic leukemia, myelodysplastic syndrome and other diseases can also cause neutropenia.

matters needing attention

The reduction of white blood cells brings great pain to patients, so healthy people must protect their internal organs, and can often do regular examination. Patients with chronic leukocytes need not take medicine if they are followed up for a long time and their blood picture is stable. Avoid overwork, work overtime, pay attention to the change of the weather, and prevent the disease caused by exogenous pathogens.