Is megalymphadenosis a tumor

summary

Normal people will become very nervous as soon as they hear about tumor, because tumor is a kind of disease which is very difficult to treat, and it will also endanger the lives of patients. Now there are many clinical cases and special images of tumor. Let's talk about whether giant lymphoproliferative disease is a tumor.

Is megalymphadenosis a tumor

First: Castleman's disease (CD), also known as vascular follicular lymphoid hyperplasia, is a rare lymphoproliferative disease. This disease was first reported by Castleman et al. In 1956. The two main clinical types are monocentric and multicentric. Unicentric type is mostly limited to a single lymph node, and multicentric type is characterized by multiple lymph node enlargement.

Second, there are three main types: hyaline vascular type, plasma cell type and mixed type. Clear vascular CD accounts for about 90% of the patients with monocentric CD, while most of the patients with multicentric CD are plasma cell type, and mixed type has both. The disease is mostly located in the chest, especially in the mediastinal region, mainly single type, rare, single type can be cured by surgery, but the treatment of multiple type is very difficult, the prognosis is poor.

Third, the pathogenesis of CD is still unknown. Recent studies have shown that the origin of CD is the excessive proliferation of B lymphocytes and plasma cells in lymph nodes caused by immunomodulatory deficiency. There are also immunological studies confirmed that the pathogenesis of CD may be related to virus infection. On the contrary, some cases reported that the occurrence of CD may not be accompanied by obvious evidence of virus infection.

matters needing attention

At present, megalymphadenosis is a very uncommon lymphoid disease, which is also very serious. Need to cooperate with the relevant treatment to maintain life and health. But a lot of clinical knowledge shows that its emergence is closely related to virus infection, patients should pay more attention.