Can pemphigus be cured

summary

Many people may not know what kind of disease pemphigus is, and some people may not have heard of such a disease, but mastering more basic knowledge always has more advantages than disadvantages. Let's talk about whether pemphigus can be cured.

Can pemphigus be cured

First, pemphigus is a chronic, recurrent, severe intraepidermal acantholysis bullous skin disease. There are antibodies against cadherin, a CA [sup] 2 + [/ sup] dependent intercellular adhesion molecule, in the patients. Therefore, there are relaxant blisters on the normal skin or mucosa, and Nissl sign is positive.

Second, the etiology of the disease has not been completely clear, now it is considered to be an autoimmune disease. The main antigen of pemphigus is desmosomes, and the main antibody is IgG. There are four kinds of IgG subtypes, and a few are IgA. The antibody binds to the epidermal cells, leading to the release of the prickles. The cDNA sequence of pemphigus antigen has obvious homology with cadherin, so pemphigus antibody also damages the adhesion function between epidermal cells, leading to the release of prickles.

Third, general supportive treatment is very important, and those with extensive damage should be given high protein diet and multivitamins. Attention should be paid to the balance of water and electrolyte. Systemic failure can be repeated small amount of blood transfusion or plasma. Strengthen nursing, pay attention to skin cleaning and hygiene, in order to reduce the secondary infection of wound, and prevent the occurrence of pressure sores.

matters needing attention

Therefore, pemphigus can be cured, which requires the joint efforts of patients and doctors, but also pay attention to local treatment, combined with systemic treatment, so the curative effect will be improved a lot, also conducive to the recovery of the disease, but also pay attention to maintain oral health.