Is hemophilia hereditary

summary

Friends have hemophilia, there will be bleeding after the injury can not stop the situation, then, hemophilia is a genetic disease? Let's talk about it.

Is hemophilia hereditary

First of all, hemophilia is a group of hemorrhagic diseases with inherited coagulation dysfunction. The common characteristics of hemophilia are the disorder of active thromboplastin production, prolonged coagulation time, slight post-traumatic bleeding tendency in life, and "spontaneous" bleeding in severe patients without obvious trauma. This is also a particularly obvious genetic disease, which can cause long-term bleeding after surgery or injury.

Secondly, hemophilia has the following conditions: 1. Hemophilia A (hemophilia A a), namely factor VIII procoagulant component (VIII: C) deficiency, also known as AGH deficiency, is a kind of sex linked recessive genetic disease, transmitted by women, male onset. 2. Hemophilia B (hemophilia B), namely factor IX deficiency, also known as PTC deficiency and thromboplastin deficiency, is also a sex linked recessive inheritance, and its incidence is less than that of hemophilia A a. However, female carriers with bleeding symptoms were more common than hemophilia A. 3. Hemophilia C (hemophilia C), that is factor XI (f XI) deficiency, also known as PTA deficiency, thromboplastin precursor deficiency. It is a rare hemophilia. It is an autosomal incomplete recessive inheritance and can be affected by both men and women. There was no difference in the incidence among different races and regions. Hemophilia A accounted for 85%, hemophilia B 15%, and hemophilia C was rare.

Finally, its genetic law is the same as that of color blindness, which is also an X-linked recessive genetic disease. Its genetic characteristics are: even if the parents are normal people, not hemophilia patients, their sons may inherit hemophilia, but their daughters will not - as long as the mother is a gene carrier.

matters needing attention

Hemophilia in pregnancy need to be prevented, especially in premarital screening should pay attention to, in addition, after pregnancy also need prenatal diagnosis, many aspects of prevention.