Can infection cause Parkinson's disease

summary

Parkinson's disease is one of the most common neurodegenerative diseases. Epidemiology shows that the disease is more common in the elderly. Many elderly people do not understand the examination methods of Parkinson's disease and have doubts about their own conditions. Moreover, many patients mistakenly believe that Parkinson's disease is infectious. Here are some introductions about the etiology of Parkinson's disease.

Can infection cause Parkinson's disease

1、 Infection, encephalitis is one of the main causes of Parkinson's disease. Parkinson's disease (PD) occurs due to the extensive destruction of brain tissue by virus after infection with encephalitis A and viral encephalitis (herpes simplex virus and cytomegalovirus), the damage of substantia nigra striatum cells and dopamine neurons, and the reduction of dopamine content. 　　

2、 Toxic factors: studies have found that some pesticides and industrial toxins in the environment are also toxic to substantia nigra cells, causing degeneration and damage of dopaminergic neurons in substantia nigra cells, so as to reduce the toxicity It reduces the ability of the substantia nigra to synthesize dopamine and causes Parkinson's disease. Mercury, manganese, chloride, sulfur dioxide, carbon monoxide poisoning Parkinson's disease. The incidence rate of Parkinson's disease increased significantly among the people exposed to polluted river water, pond water and well water for a long time, who often contacted pesticides and pesticides, workers and surrounding people in chemical plants, steel mills, paper mills and rubber factories. This shows that environmental factors play a certain role in the pathogenesis of Parkinson's disease. 　　

3、 Genetic factors: some cases of Parkinson's disease have obvious family history. It has been found that 10 kinds of genes can cause Parkinson's disease. The most common gene defect is the parkin gene on the sixth pair of chromosomes. The mutation of this gene can cause autosomal recessive Parkinson's disease. Some researchers believe that Parkinson's disease is not directly inherited, but the genetic predisposition of Parkinson's disease Sensibility.

matters needing attention

Improper or excessive use of drugs, long-term use of antipsychotics, can also cause symptoms and signs of Parkinson's disease.