How does membranous nephropathy return a responsibility

summary

Recently, I always feel my low back pain, but I don't know exactly where it is. After a few days of rest, I didn't get better, which made me very upset. My husband immediately brought me to the hospital for examination after he knew, and the doctor said that I had membranous nephropathy. Today, I'd like to talk about membranous nephropathy.

How does membranous nephropathy return a responsibility

First: membranous nephropathy, also known as membranous glomerulonephritis, is characterized by small kidneys. Diffuse deposition of immune complexes under the epithelial cells of bulbar basement membrane accompanied with diffuse thickening of basement membrane. Nephrotic syndrome or asymptomatic proteinuria is the main clinical manifestation. Membranous nephropathy can be primary or secondary to a variety of diseases, such as infectious systemic diseases, drug therapy and malignant tumors.

Second: most of membranous nephropathy onset slowly, generally without a history of prodromal upper respiratory tract infection, a few patients showed asymptomatic proteinuria, most patients (70% ~ 80%) had a lot of proteinuria, manifested as nephrotic syndrome, Mn incubation period is generally a few weeks to a few months, during which the glomerular epithelial deposition gradually formed, but the increase in urinary protein excretion is not enough to form clinical symptoms In 80% of the patients, edema was the first symptom.

Third: 20% of the patients were diagnosed with proteinuria. The urinary protein excretion of idiopathic membranous nephropathy is usually 5-10g per day, which can be as high as 20g / d. most of them are non selective proteinuria. The amount of urinary protein fluctuates greatly due to different protein intake, body position, activity and renal hemodynamic indexes every day. Generally, there is no gross hematuria. 50% of adults and most children have microscopic hematuria, which is similar to many acute diseases There was no hypertension in the early stage of the disease.

matters needing attention

Many friends have never heard of membranous nephropathy. In fact, membranous nephropathy is a kind of nephropathy. Like other types of kidney disease, it needs to be treated and recuperated slowly, and can be cured after a period of treatment.