What are the treatment options for lung cancer

summary

Grandma lives in her hometown. When she called her a few days ago, she told me that she was a neighbor of our family and an old granny. Because she was not well, her children took her to the hospital for examination, but she got lung cancer. Let's talk about the treatment plan for lung cancer.

What are the treatment options for lung cancer

First: targeted therapy targeted therapy for traditional chemotherapy is the role of drug therapy in new sites, in fact, chemotherapy and targeted therapy are drug therapy, chemotherapy is the role of each site in the cell, such as each cell has a different mitotic phase. But now on the road of chemotherapy, the original cytotoxic drugs have come to the bottleneck, and it is very difficult to go up again. Many new drugs have not come out. In fact, tumor growth is not only a process of mitosis in cells, but also other processes, such as angiogenesis around cells, the impact of changes in the environment around cells on tumors. Malignant tumors need to start and signal transduction to cause infinite proliferation process. If this signal transduction is blocked, cell proliferation can be prevented. The drugs developed for these targets are now relatively hot targeted drugs.

Second: radiotherapy (1) treatment principle: radiotherapy is the best for small cell carcinoma, followed by squamous cell carcinoma and adenocarcinoma. However, small cell carcinoma is prone to metastasis, so large irregular field irradiation is often used. The irradiation area should include the primary mediastinum, bilateral supraclavicular area, even liver, brain and other parts. Squamous cell carcinoma has moderate sensitivity to radiation. The lesions are mainly local invasion, and the metastasis is relatively small, so radical treatment is often used. Adenocarcinoma is not sensitive to radiation and easy to metastasize, so radiotherapy alone is rarely used. The sensitivity of tumor to radiation is affected not only by pathological types, but also by tumor size, differentiation degree of tumor cells, proportion of tumor cell population, tumor bed and other factors. Therefore, before making radiotherapy plan, we should carefully analyze, comprehensively weigh the advantages and disadvantages, and can not easily draw a conclusion.

Third: chemotherapy has developed rapidly and been widely used in the past 20 years. According to the current data at home and abroad, the curative effect of chemotherapy on small cell lung cancer is certain, no matter in the early or late stage, there are even a few reports of radical treatment, and it also has certain curative effect on non-small cell lung cancer, but it is only palliative and needs to be further improved. In recent years, the role of chemotherapy in lung cancer is no longer limited to inoperable advanced lung cancer, but often included in the comprehensive treatment of lung cancer as systemic treatment.

matters needing attention

With the discovery of tumor markers and the definition of evaluation criteria, gene detection and genotyping are widely used in tumor treatment. It plays an important role in disease screening, classification and staging, prognosis judgment, progress evaluation and treatment prediction. More than 50% of the pathogenic genes of NSCLC have been identified, and the two most important driving genes are KRAS and EGFR. Others include ALK, HER2, BRAF, Akt, etc. KRAS mutations are common in adenocarcinoma.