What is tropical stomatitis diarrhea?

summary

Tropical stomatitis diarrhea occurs in tropical residents, and is most common in South America, Africa, India and other Southeast Asian countries. In recent years, this disease has been classified as "infectious malabsorption" and divided into parasitic (giardiasis) and non parasitic (tropical stomatitis diarrhea).

What is tropical stomatitis diarrhea?

The etiology has not yet been fully elucidated. It is now considered that the chronic small intestinal infection caused by one or more pathogenic microorganisms or parasites has no clear relationship with the diet of wheat gluten. The disease is epidemic and seasonal, and the treatment with broad-spectrum antibiotics is effective, but no pathogen is found in feces, intestinal contents and intestinal mucosa. Nutritional deficiency, such as protein, vitamin B and folic acid, may be related to the disease.

The patient has fatigue, abdominal pain, diarrhea, stool 1~2 times a day or more than ten times, feces volume is large, paste, light, stench, oily foam. About 30% of the cases have steatosis. Hypoalbuminemia, oral protein tolerance test showed delayed absorption. 50% of the patients had abnormal glucose tolerance, and about 90% of the patients had decreased urine output in xylose absorption test. Vitamin A and B12 absorption tests were also abnormal.

First of all, give a nutritious diet, appropriate fluid, correct electrolyte imbalance. The patients with excessive diarrhea were given antidiarrheal. Vitamin B12, folic acid treatment time to continue for one year. At the same time, they were treated with antibiotics, tetracycline was taken orally 4 times a day for 1 month, and then changed to 2 times a day for 5-6 months. Sulfonamides are also effective, such as sulfothiazole succinate. After treatment, anemia and glossitis quickly recovered, appetite improved, body weight increased, intestinal mucosal lesions improved, intestinal mucosal enzyme activity increased. In some cases, the response to treatment is very slow, the symptoms and malabsorption last for a long time, so the treatment time is longer.

matters needing attention

It may be related to bacterial infection. It mainly occurs in residents or tourists in India, Southeast Asia and tropical Central America. Develop good hygiene habits, wash hands thoroughly with soap before and after meals; Ensure drinking clean water; Do not eat bad food, raw fruit to wash; It's also important to be optimistic and exercise more. Avoid contact and infection between personnel.