Is leukaemia chronic disease

summary

My brother had a fever three years ago. The doctor suggested that he go to a big hospital for a comprehensive diagnosis. As a result, he was diagnosed with leukemia. The doctor said that he needed a bone marrow transplant, but he didn't find a suitable bone marrow. It wasn't long before his brother died. I am very sad for this, and I have consulted a lot of information about leukemia. I would like to share with the majority of netizens that leukemia is a chronic disease.

Is leukaemia chronic disease

First: leukemia is divided into acute leukemia and chronic leukemia, can also be divided into myeloid leukemia (also known as myeloid leukemia) and lymphocytic leukemia, and so on. "Acute myeloid leukemia" has been diagnosed as acute, which of course belongs to acute leukemia, but acute myeloid leukemia can be transformed from chronic myeloid leukemia. If CML enters the acute phase, that is, it turns into acute leukemia, the prognosis will be worse. So acute myeloid leukemia is certainly not a chronic disease, but it may have been a chronic disease.

Second: chronic leukemia, divided into chronic myeloid leukemia and chronic lymphocytic leukemia. Chronic myelogenous leukemia (CML) is a kind of leukemia with relatively slow onset and development. He is a malignant proliferative disease originated from bone marrow pluripotent hematopoietic stem cells, characterized by myeloid progenitor cell pool expansion, myeloid cell lines and their progenitor cells overgrowth. More than 90% of the cases have CML marker chromosome. The molecular biological basis of Ph1 chromosome is BER / abl gene rearrangement.

Third: acute leukemia (AL) is a malignant clonal disease of hematopoietic stem cells. At the onset of the disease, abnormal primordial cells and immature cells (leukemia cells) in bone marrow proliferate in large numbers, accumulate in bone marrow and inhibit normal hematopoiesis, and extensively infiltrate extramedullary organs such as liver, spleen, lymph nodes and so on. The manifestations were anemia, hemorrhage, infection and infiltration. According to the type of cells involved, Al can be divided into acute lymphoblastic leukemia (all) and acute myeloid leukemia (AML). The incidence rate of AML in China is about 1.62/10, while ALL is about 0.69/10 million. AML is more common in adults and all is more common in children. Without special treatment, the average survival time of acute leukemia is only about 3 months, and those with short survival time even die a few days after diagnosis. After modern treatment, many patients have achieved remission and long-term survival, or even cure.

matters needing attention

The general treatment principle is to eliminate as many leukemic cell population as possible and control the proliferation of leukemic cells, relieve various clinical manifestations caused by leukemic cell infiltration, in order to obtain complete remission.