The harm of immune infertility

summary

I'll be married for one year now. Unfortunately, I didn't get pregnant. Looking at my friends with their children, I felt very bad. Later, I insisted on going to the hospital for infertility examination. I had a little gynecological inflammation. After treatment for a period of time, I'm more practical. Let's talk about the harm of immune infertility.

The harm of immune infertility

First: affect sperm activity, prevent sperm through cervical mucus, hinder sperm activity. There is cytotoxic reaction, causing sperm death or affecting sperm activity. It will affect sperm metabolism and sperm contractile protein function.

Second, the impact of embryonic development, such as bilateral genital tract obstruction, testicular biopsy, varicocele, etc., will cause testicular blood testicular barrier damage, testicular heat or damage, resulting in sperm antibody formation, leading to female infertility.

Third: the use of rebound therapy. According to the physiological characteristics of testosterone, the application of high-dose testosterone can inhibit the spermatogenic epithelium first, and then stop testosterone, so that the spermatogenic epithelium can produce more sperm after removing the inhibition, which is called testosterone rebound therapy. When the number of spermatozoa decreased, the antibody titer also decreased or disappeared. When the number of spermatozoa rebounded and the antibody did not increase significantly, the chance of pregnancy increased.

matters needing attention

In vitro fertilization: the sperm and egg are cultured and fertilized in vitro, and implanted into the uterine cavity 3-5 days after fertilization. Therefore, the sperm does not need to contact with the female genital tract containing sperm antibody before fertilization. After fertilization, due to the protective effect of zona pellucida, sperm antibody can not attack the pregnant egg, and then the pregnant egg is infected.