How to diagnose ichthyosis in infants

summary

Recently, the baby's body is very dry, and gradually becomes very black, and it looks like fish scale. I went to the hospital to have an examination. The doctor said it was ichthyosis, and now I'm taking medicine to treat it, and the symptoms have been alleviated. How can I make a diagnosis of infant ichthyosis? Now let's talk about how to diagnose infant ichthyosis.

How to diagnose ichthyosis in infants

First, direct immunofluorescence. Direct and indirect immunofluorescence examination showed that the immune complexes deposited on the dermis side. This method can be used to differentiate EBA from bullous pemphigoid, which is deposited on the epidermis.

Second, immunoelectron microscopy of the skin around the lesion showed that the immune reactants deposited in the dense plate of basement membrane or the anchor fibers below it, which was the most reliable method to distinguish EBA from bullous pemphigoid.

Third, the antigen of EBA (glycoprotein of molecular weight, which is proved to be the same substance as procollagen, and the latter is the main protein component of anchor fiber) was determined by Western blotting. EBA can be distinguished from other bullous skin diseases.

matters needing attention

We suggest that we should pay attention to: ichthyosis patients need to pay attention to protein supplement. Protein is an indispensable nutrient for the formation of muscle, ligament and bone. After the attack of ichthyosis, the daily loss of different degrees of nutrition, to timely supplement, appropriate to eat some pig liver, chicken, cheese, soybeans and its products.