How long can germinoma live
summary
My cousin went to the library that day to test how long my germ cell tumor could survive. I was hit hard at that time and immediately went to check. Now I'd like to express my experience on how long germ cell tumor can live.
How long can germinoma live
Germinomas are derived from primordial germ cells, most of which are located in the pineal region, followed by the suprasellar cistern. Most of the tumors occurred in male adolescents, while most of the tumors located in suprasellar germinoma were in females. Germ cell tumors are very sensitive to radiation. The tumor usually has no capsule, calcification, hemorrhage, necrosis or cystic change. It is a low-grade malignant tumor with infiltrative growth and metastasis in different degrees and forms. It is easy to plant and spread to subarachnoid space and ventricular system. Histologically, the tumor mainly contains two cell components: epithelioid cells and lymphoid cells.
The etiology of intracerebral germ cell tumors is not clear, and family history is rare. Germ cell tumors have been reported in the mediastinum and brain of patients with Klinefelter syndrome (47, XXY, 47 chromosomes, 2 x and 1 y sex chromosomes). The typical characteristics of these patients are small testis, vitreous degeneration of seminiferous tubules, and azoospermia. It is speculated that the germ cell tumors in mediastinum and intracranial region are caused by the variation of primordial germ ridge differentiation, which leads to the migration and differentiation of germ cells and the tendency of malignancy.
Chromosomal abnormalities often occur in patients with intracerebral germ cell tumors, including non random chromosomal abnormalities and structural heterotopia. In testicular germ cell tumors, 80% of them are characterized by chromosomal structural abnormalities. The short arm of chromosome 12 is isoarm (i12p). Many non germ cell tumors and extragonadal germ cell tumors also have i12p abnormalities.
matters needing attention
About how long a germ cell tumor can live. Germ cell tumor can be treated by radiotherapy, but it is easy to metastasize along the cerebrospinal fluid, so it needs regular review. If you are too young, consider whole brain and whole spinal cord radiotherapy as appropriate. It is suggested to take ginsenoside Rh2 after operation to improve immunity, inhibit the proliferation of cancer cells and reduce postoperative complications.
