Causes of hyperuricemia after renal transplantation

summary

Hyperuricemia is a disease caused by the disorder of purine metabolism in human body. Any factor that affects the production and (or) excretion of serum uric acid can lead to the increase of serum uric acid level. But don't panic, let me talk about the reason of high uric acid after kidney transplantation.

Causes of hyperuricemia after renal transplantation

Reason 1: excessive intake of purine: the high level of blood uric acid is directly proportional to the purine content in food. 50% of RNA and 25% of DNA in food should be excreted in the form of uric acid in urine, which is also one of the reasons for the high level of serum uric acid. Strict restriction of purine intake can reduce the content of serum uric acid.

Reason 2: the human body has its own circulation process. The purine metabolism in the body will form uric acid after the oxidation of renal function, and then excrete it out of the body. However, if you eat a lot of purine containing food, it will cause the increase of uric acid. If you can't excrete the excess uric acid, it will lead to excessive uric acid.

Reason 3: the metabolic disorder of purine substances in the body leads to the reduction of uric acid excretion. 90% of patients with persistent high uric acid have abnormal renal function in handling uric acid. The decrease of uric acid secretion may be related to the decrease of glomerular filtration rate, renal tubular secretion or renal tubular reabsorption.

matters needing attention

The above is the answer to the reason of high uric acid after renal transplantation. Eat properly. Appropriate aerobic exercise, must not do strenuous exercise, in order to avoid joint fatigue. It's best to choose aerobic exercise such as swimming, Taijiquan and table tennis to reduce weight.