What about the short longitudinal groove?
summary
Short longitudinal sulcus is a special appearance of digolger syndrome after birth. It is a kind of disease caused by thymus hypoplasia, lack of T lymphocytes in peripheral lymphoid tissue and blood circulation or T cell dysfunction, It is the result of the development defect of the third and fourth pharyngeal cleft sac. It belongs to primary cellular immune deficiency disease. So what about the short longitudinal sulcus?
What about the short longitudinal groove?
Most patients with complete DiGeorge died in infancy. Some patients with incomplete DiGeorge had spontaneous improvement of T cell function and a longer survival time. For hypoparathyroidism and hypocalcemia, vitamin D and calcium should be used for a long time. In severe cases, fetal thymus tissue can be transplanted to improve immune function. In China, 3 cases of immunodeficient patients were treated with fetal thymus culture for about 14 days. Bone marrow or lymphoid tissue can also be transplanted, but the effect is uncertain. Congenital cardiovascular malformations can be treated surgically.
This disease should be differentiated from other causes of thymic insufficiency. It is a genetic disease, that is, thymus dysplasia, but not parathyroid insufficiency. Laboratory examination (1) peripheral blood lymphocytes decreased, especially T cells decreased, the percentage of B cells increased（ 2) The cellular immune function decreased in varying degrees（ 3) Humoral immune function is uncertain, serum immunoglobulin is often not low（ 4) The content of blood calcium decreased（ 5) Parathyroid hormone level decreased.
The etiology of this disease is congenital immune deficiency caused by the abnormal development of the first to the sixth pair of pharyngeal sacs in the early embryo. At the 6th to 10th week of the embryo, the thymus, parathyroid gland, part of the face, aortic arch and heart tuberculosis develop from the cell components of the first to the sixth pair of pharyngeal sacs. At the 12th week of pregnancy, the thymus migrates to the chest
matters needing attention
It is suitable to eat high calorie food; It is suitable to eat food rich in protein; It is suitable to eat foods rich in vitamins; Appropriate supplement of calcium and phosphorus. Chinese cabbage is sweet, light, and low in calories β- Carotene, iron, magnesium, can enhance the calcium absorption of the required ingredients, in addition, the potassium in Chinese cabbage will be salt out of the body, has diuretic effect.
