What are the causes of cerebral perforating malformation?

summary

Brain penetrating malformation (BPD) is an embryonic dysplasia, which may be related to maternal infection or nutritional disorders. Pathologically, a cystic cavity is formed in the brain, lined with ependyma, and most of it communicates with the ventricle or subarachnoid space. What are the causes of brain perforating malformation? Let's talk about it now.

What are the causes of cerebral perforating malformation?

Congenital dysplasia is the most common type of brain perforating malformation, which is mainly caused by the developmental disorder of nervous system in embryo. Acquired cerebral perforating malformation is mainly associated with neonatal intracranial hemorrhage, hypoxic-ischemic encephalopathy, brain injury and cerebrovascular disease.

When the intraventricular pressure increases, or in the process of scar formation, the ventricles expand to the place of encephalomalacia. Cerebrospinal fluid may accumulate in the cyst like swelling of brain tissue, or penetrate the brain parenchyma and connect with subarachnoid space or subdural space. Most of them were found in frontal or temporal horn of lateral ventricle, occasionally in occipital horn. The cystoid enlargement varies in shape and size, and the largest one can fill the whole half of the cranial cavity.

Although brain perforating malformation is benign, it has potential harm. Once diagnosed, it should be operated as soon as possible. The patients without intracranial hypertension and moderate or severe hydrocephalus can be treated with conservative methods temporarily.

matters needing attention

Prenatal diagnosis is the best prevention method. CT scan can directly show the existence and types of cerebral perforating malformation. It is of great significance to understand the size, location, shape, number of cysts, the choice of treatment, prognosis and differential diagnosis