What about immune deficiency?

Update Date: 2022-07-30 Source: Network

summary

Immune deficiency is a kind of disease characterized by repeated infection or severe infection, which is caused by the deficiency of human immune system development or immune response disorder. Let's share my experience with you.

What about immune deficiency?

It accounts for 50% - 70% of congenital immunodeficiency. The defect occurs in the stage of B lymphocyte progenitor cells, B lymphocytes can not mature, so they can not produce antibodies. Therefore, the main feature of the disease is the decrease or deletion of immunoglobulin level. The defect of this kind of immunoglobulin can be the decrease of all kinds of immunoglobulin, or the decrease of one class or subclass of immunoglobulin. Sexual hypogammaglobulinemia (Bruton syndrome), selective IgA, IgM and IgG subclass defects are all of these diseases.

It accounts for 5% ~ 10% of congenital immunodeficiency. It is mainly due to congenital thymus hypoplasia that the number of T cells is reduced. It can also lead to T cell dysfunction due to the lack of some enzymes or membrane glycoproteins. DiGeorge syndrome (congenital thymic dysplasia) is the representative of this kind of disease.

Secondary immunodeficiency disease refers to the temporary or lasting damage of immune system caused by other diseases (such as chronic infection), radiation, long-term use of immunosuppressants and nutritional disorders, resulting in low immune function. Secondary immunodeficiency can be cellular immunodeficiency, humoral immunodeficiency, or both. According to the different causes of the disease, secondary immunodeficiency can be divided into two categories: secondary to some diseases and iatrogenic immunodeficiency. 1. Immune deficiency secondary to some diseases

matters needing attention

In daily life, eat more fruits and vegetables, keep optimistic mood, pay attention not to fatigue, pay attention to the recovery of the body, in addition, if there are any symptoms should go to the hospital for examination, and corresponding treatment, these are to actively do.