Symptoms of drug-induced renal injury?

summary

As the saying goes, medicine is divided into three parts. Medicine is like a double-edged sword, in the treatment of disease at the same time, more or less may cause harm to the human body. As the most important metabolism and excretion organ of drugs, the chance of kidney injury is also greatly increased. Symptoms of drug-induced renal injury? Let's talk about it

Symptoms of drug-induced renal injury?

Drug induced acute renal damage is usually manifested as ARF after a single or continuous administration for several days. Most of the patients show renal parenchymal acute renal damage. The main clinicopathological features are acute interstitial nephritis (AIN), and some of them show ATN, sometimes both of them coexist.

A few patients may show functional (prerenal) or obstructive (Retrorenal) ARF. Some drugs involved glomerulus or microvascular, can appear rapidly progressive nephritis syndrome, nephrotic syndrome, small vasculitis or thrombotic microvascular disease.

Pathological manifestations included minimal change nephropathy, membranous nephropathy and ANCA associated vasculitis. Different drugs can lead to the same pathological changes, but a drug can also lead to different pathological types.

matters needing attention

In addition, it should be noted that when people have a cold and fever, their appetite is poor, they drink less water, the concentration of drugs in the blood is higher, and the damage to the kidney is greater. Therefore, if you have diarrhea or fever, and you drink very little water and keep pulling, you must pay attention to rehydration or infusion.