Can congenital giant pigmented nevus be treated?

summary

Congenital giant nevus is a kind of melanocytic nevus. It is a rare benign skin tumor. Its characteristic is wide range. The tissue defect after resection can not be repaired by adjacent tissue. The incidence rate of facial nevus is close to 1/10000 because of its serious psychological barrier. Can congenital giant pigmented nevus be treated?

Can congenital giant pigmented nevus be treated?

1. Chemical exfoliation began in the folk, its main principle is to destroy the nevus cells of the skin with chemical corrosives. Now there are mainly a-hydroxy acid (AHA), carbolic acid, trichloroacetic acid (TCA), resorcinol and so on. Some experts used multiple stripping to treat 21 cases of congenital giant nevus, but this method, especially after infection, is prone to scar. In order to prevent pigmentation in the stripping area, 4% hydroquinone ointment was applied in the operation area at night and shading in the daytime. Carbolic acid is the earliest stripping agent with deep stripping layer, but it has toxic effect on heart and kidney. Although trichloroacetic acid is less toxic than carbolic acid, its stripping depth is less than that of carbolic acid. AHA is the mildest stripping agent with the shallowest stripping depth and less adverse reactions. The utility model has the advantages of convenient use, reliable curative effect, and can be applied in outpatient service.

2. After removing the damaged part of nevus with ball mill, oil gauze or other dressings should be used to bandage. Infants should be rehydrated and infection should be prevented according to the same area of burn. Early treatment is the key to this method. Before the nevus cells migrate to the deep dermis within one year old, the treatment effect is the best, but its long-term effect needs to be further observed.

3. With the development of medical laser treatment technology, since 2004, laser has played an important role in the treatment of congenital giant nevus. At present, ultrashort high-energy pulsed CO2 laser, Q-switched ruby laser (qs2rl) and Q-switched Nd: YAG laser (qsnyl) have successfully treated congenital giant nevus. Laser irradiation can remove the epidermis and superficial dermis, and the wound can be healed by re epidermization. It can be regarded as a safe and effective method for the patients with extensive area that can not be removed surgically.

matters needing attention

1. Non operative therapy includes liquid nitrogen freezing, laser, electrolysis, electrocautery, high-frequency electrotome, trichloroacetic acid, carbolic acid and other chemical corrosion methods. Its principle is to use various methods to destroy the local tissue of the lesion, gradually fall off, and rely on the regeneration and repair of the surrounding tissue. Although the operation can be avoided, it is difficult to master the depth of tissue destruction, too shallow treatment is not complete and the formation of stimulating factors, too deep will leave depressed scars, and the local skin color is different from the surrounding tissue after treatment. 2. Surgical treatment of any type of nevus, regardless of size, can be applied. The curative effect is stable and reliable, and further pathological examination can be done after cutting the tissue.