Efficacy of spironolactone capsules?

Update Date: Source: Network

summary

Spironolactone tablets are commonly used in the treatment of edematous diseases, as well as congestive edema and other edematous diseases. Then it can be used as a help drug for the treatment of hypertension. Primary aldosteronism can be used for this drug treatment. Finally, the prevention of hypokalemia can enhance diuresis and prevent hypokalemia. Spironolactone tablets are very effective in the treatment of edema, which is liked by many doctors. However, it should be noted that taking spironolactone tablets for a long time can lead to female breast pain and coarsening voice. Efficacy of spironolactone capsules? Now let me tell you something.

Efficacy of spironolactone capsules?

The most common adverse reactions of spironolactone tablets are hyperkalemia, especially when used alone or combined with thiazide diuretics, the incidence of hyperkalemia is still relatively high, and it is often manifested as arrhythmia, so it is necessary to closely follow up the blood potassium and ECG during medication; It can also cause nausea, vomiting and diarrhea; It's also said that it can cause peptic ulcer.

Spironolactone tablets also have effects on human endocrine system. Long term use of spironolactone tablets can cause breast development, impotence and low sexual function in men. In women, it can cause breast swelling and pain, voice thickening, hair increasing, menstrual disorders and decreased sexual function; The effect on the central nervous system is that long-term or high-dose administration of the drug can lead to walking uncoordinated.

It should be noted that spironolactone tablets should be used from the minimum amount to reduce the occurrence of side effects such as electrolyte disturbance. Once a day, should take medicine in the morning, lest nocturnal micturition frequency increases. The blood potassium concentration of patients should be known before medication, but in some cases, the blood potassium concentration does not represent the total amount of potassium in the body, which can be used as a judgment standard.

matters needing attention

Patients need to pay attention to the slow action of the drug, and maintain a longer time, when combined with other diuretics, to take other diuretics 2-3 days. At the time of withdrawal, the drug should be stopped 2-3 days before other diuretics. Hyperkalemia should be stopped immediately.