What harm does proteinuria have

summary

May physical examination urine protein is normal, November physical examination urine protein 1 +, other indicators are normal, renal function is normal, liver function is normal, now it is much better, here the urine protein what harm experience to write out to share with you.

What harm does proteinuria have

Hazard 1: urine protein has toxic effect on glomerular mesangial cells. After patients enter renal failure, there will be a large number of plasma protein deposition in glomerular mesangial area. The deposition of these macromolecular substances in mesangial area can cause mesangial cell damage, mesangial cell proliferation and mesangial matrix formation increase, leading to glomerulosclerosis.

Harm 3: urine protein can damage the renal tubulointerstitium. A small amount of small molecular protein filtered by normal glomerulus is reabsorbed by epithelial cells close to renal tubules and decomposed in lysosomes. Under pathological condition, the increase of glomerular permeability makes a large amount of plasma protein leak into the renal tubules, and the excessive reabsorption of albumin by proximal renal tubular epithelial cells leads to the increase of lysosomal activity in the cytoplasm, which can cause cell damage.

Harm 3: a large amount of proteinuria can increase the protein reabsorption of renal tubules, promote the production of ammonia, and the production of ammonia in renal tissue also plays a role in progressive interstitial lesions. In addition, it needs extra energy to reabsorb and digest a large amount of protein, which can cause tubular cell hypoxia, increase the production of oxygen free radicals and cause tubular cell damage.

matters needing attention

Warm reminder: Patients with urinary protein, we should pay attention to the impact of diet on patients with urinary protein, mainly to achieve light based diet, promote the recovery of urinary protein, in addition, it is suggested that patients with urinary protein should eat more vegetables and fruits, eat less spicy food. It is necessary to pay attention to the treatment of urinary protein, because if the treatment measures are effective, I believe it can achieve good treatment effect. It is also suggested that in the treatment of urinary protein disease, we should also attach great importance to some nursing problems related to life, so as to promote the recovery of urinary protein.