Pituitary tumor symptoms?

summary

Pituitary adenomas are a group of tumors arising from the residual cells of anterior and posterior pituitary and craniopharyngeal epithelium. About 10% of intracranial tumors have obvious clinical symptoms. Male slightly more than female, pituitary tumor usually occurs in young adults, often affect the patient's growth and development, reproductive function, learning and working ability. The clinical manifestations were abnormal hormone secretion syndrome, tumor compression of pituitary surrounding tissue syndrome, pituitary apoplexy and other manifestations of anterior pituitary dysfunction. Pituitary tumor symptoms? Let's talk about it

Pituitary tumor symptoms?

Excessive hormone secretion syndrome, such as acromegaly caused by excessive growth hormone; Hypohormonal syndrome. When the nonfunctional tumor is enlarged and normal pituitary tissue is destroyed, amenorrhea occurs due to decreased gonadotropin secretion. Infertility or impotence is often the earliest and most common.

Pituitary abscess is characterized by recurrent metastatic fever, headache, obvious visual impairment, and other cranial nerve damage. The disease usually develops rapidly. The volume of clinical imaging pathological changes is usually small, which is not consistent with clinical symptoms. The soft tissue structure around sella turcica was obviously strengthened.

Craniopharyngioma mostly occurs in young children and young people, with slow pathological changes. In addition to vision and visual field disorders, there are also clinical manifestations of hypopituitarism and hypothalamus involvement, such as developmental arrest, undeveloped sexual organs, obesity and diabetes insipidus. Large tumors show symptoms of increased intracranial pressure. Most of the tumors were cystic and calcified. Most of the tumors are located in the suprasellar region, and the pituitary tissue is located at the bottom of the intrasellar region.

matters needing attention

For prolactin secreting pituitary tumors, more than 90% of patients (whether microadenomas or macroadenomas) can use dopamine agonists (short acting agent bromocriptine, long acting agent carbergolin) to control the PRL level and reduce the tumor volume. Only those prolactinoma patients who are allergic or intolerant to these drugs, whose acute symptoms caused by tumor compression need emergency surgical decompression, or whose patients are not willing to accept surgical treatment, can choose surgical treatment. During the treatment of bromocriptine, the dose of bromocriptine should be gradually increased until the serum PRL level is reduced to normal level, and the dose should be adjusted for long-term maintenance treatment.