What can bone marrow transplantation treat muscular dystrophy

Update Date: Source: Network

summary

Generally speaking, muscular dystrophy is a group of hereditary myopathy. The disease progresses rapidly, and there is no good treatment at present, which brings a great burden to patients and their families. Let's talk about bone marrow transplantation for the treatment of muscular dystrophy.

What can bone marrow transplantation treat muscular dystrophy

First: some people think that muscular dystrophy is the lack of nutrition of children, or that children are too poor, so we should vigorously increase nutrition for children and encourage them to eat more. In fact, excessive intake of nutrition, excessive eating and reduced exercise can cause obesity, which will further reduce the patient's ability to act and bring great difficulties to parents and patients. The patient's diet should be low calorie, low fat, low sugar, sufficient protein, high vitamin, can be a small number of meals. Dyskinesia occurred earlier in patients with pseudoobese progressive muscular dystrophy.

Second: progressive muscular dystrophy is a group of hereditary skeletal muscle degeneration diseases. The main pathological features are skeletal muscle fiber degeneration and necrosis. The main clinical manifestations are slow progressive muscle atrophy and muscle weakness. Some types can also involve the heart and skeletal system. Traditionally, it is divided into pseudohypertrophic muscular dystrophy, facioscapulohumeral muscular dystrophy, limb girdle muscular dystrophy, emery Dreifuss muscular dystrophy, oculopharyngeal muscular dystrophy, ocular muscular dystrophy, distal muscular dystrophy and congenital muscular dystrophy. It can be divided into sex linked recessive inheritance, autosomal dominant inheritance and autosomal recessive inheritance.

Third, there are satellite cells in normal skeletal muscle, which regenerate and differentiate into new muscle cells after muscle injury. When muscle cells are cultured in vitro, satellite cells can develop into myoblasts. A large number of these cultured myoblasts are injected into diseased muscles to fuse normal myoblasts with diseased myocytes of DMD, so as to achieve the purpose of treatment, which is called myoblast transplantation.

matters needing attention

The addition of patients with muscular dystrophy should give the best psychological support to the patients, so that the patients and their families can face the reality and maintain a positive attitude, and then the patients should exercise properly, so as to prevent the deterioration of the disease.