What examination does myasthenia gravis need to do

summary

Another important way to treat patients with myasthenia gravis is to treat patients with dyspnea. When patients emerge with myasthenia gravis, it is very difficult to expectorate. It is very easy to merge with pulmonary infection, and dyspnea can emerge. As a more complex disease, myasthenia gravis need to do what examination can?

What examination does myasthenia gravis need to do

Examination 1: myasthenia gravis is a chronic autoimmune disease caused by transmission dysfunction between nerve and muscle joints. The main clinical feature is that local or whole striated muscles are prone to fatigue and weakness. You should see neurology.

Examination 2: electromyogram examination: stimulate a motor nerve at a frequency of 2-3hz for 5 times, which is called repetitive frequency stimulation test. The amplitude of muscle evoked potential decreases by 10% or more after biting. If two or more proximal or distal muscles were examined, almost all patients showed positive results. The decrease of amplitude was caused by the decrease of the minimum release unit of acetylcholine released by nerve endings. Single fiber electromyography, in the process of active muscle contraction, when comparing the action potential of muscle fibers with similar distance in the same motor unit, the low amplitude and relatively long-term EPP of patients with myasthenia gravis can cause the prolongation of potential interval of some muscle fibers and intermittent block of action potential gap.

Examination 3: serological test. At present, radioimmunoassay and enzyme-linked immunosorbent assay are used to detect acetylmuscarinic receptor antibody. The method of radioimmunoassay was to label muscarinic acetylcholine receptor with Bungarus Bungarus toxin, and then to detect acetylcholine receptor antibody. A bungarotoxin irreversibly binds to acetylcholine receptor subunit a. The positive rate of acetylcholine receptor antibody varies with the disease and course of disease. In general, the positive rate of myasthenia gravis is the highest in severe and moderate types, about 95%; in mild type, the positive rate of antibody is about 80%; in ocular type, the positive rate is the lowest, about 50%. In some patients, the antibody was negative or the titer was low at the beginning of the disease. With the extension of the disease or the change of the disease, the antibody turned positive or the titer increased. On the whole, the antibody titer and the severity of the disease were not consistent. However, with the increase of the number of plasma exchange, the antibody titer decreased and the clinical symptoms improved.

matters needing attention

We suggest that you should pay attention to: myasthenia gravis diet 200 grams of Japonica rice, ginseng powder (or tablets) 10 grams, add water amount, first with fire boil, and then change the slow fire boil to thick, add an appropriate amount of rock sugar, stir. Mutton soup: fresh mutton stew, take soup and eat meat. Mutton is warm in nature, which can cure asthenia and invigorate Yang.