Chronic urticaria symptoms?
summary
Chronic urticaria refers to the skin, mucosa, blood vessels caused by various factors of temporary inflammatory congestion and tissue edema, the course of more than 6 weeks known as chronic urticaria. The cause is often uncertain. The clinical manifestations of the patients were wheezes and plaques on the trunk, face or limbs from time to time. Attacks range from several times a day to once a few days. Chronic urticaria symptoms? Let's talk about it
Chronic urticaria symptoms?
Most of the patients can obtain satisfactory curative effect after antihistamine treatment, and a few patients are stubborn. For refractory urticaria, the dosage can be increased or combined. H1 receptor antagonist has a strong histamine and anti-inflammatory mediators, which is effective in the treatment of all types of urticaria. The commonly used H1 receptor antagonists are diphenhydramine, cyproheptadine, chlorpheniramine, Avastin, cetirizine, mizolastine, loratadine, ebastine, azelastine and desloratadine. Two different types of H1 receptor antagonists can be used together or combined with H2 receptor antagonists (cimetidine, ranitidine). Antale has strong antihistamine, anticholinergic and sedative effects, and the antipruritic effect is also very good. It is effective for acute and chronic urticaria and cold urticaria. Doxepin is a tricyclic antidepressant, which is mainly used in the treatment of depression and anxiety neurosis. Doxepin also has strong anti H1 and H2 receptor effects. It has better effect on chronic urticaria and less side effect.
It has strong anti-inflammatory and anti allergic effects. It can stabilize mast cell membrane and lysosomal membrane, inhibit the release of inflammatory mediators and lysosomal enzymes; Constrict blood vessels and reduce exudation. It is especially suitable for acute urticaria, serological urticaria, stress urticaria and autoimmune urticaria. Commonly used drugs include prednisone and Diprospan. In case of emergency, hydrocortisone, dexamethasone or methylprednisolone were given intravenously.
When patients with chronic urticaria have autoimmune basis, the disease is repeated, and the above treatment can not achieve curative effect, immunosuppressant can be used. Cyclosporine has a good curative effect, azathioprine, cyclophosphamide, methotrexate and immunoglobulin can be used, Tripterygium wilfordii also has a certain curative effect.
matters needing attention
The attack and aggravation of chronic urticaria are related to people's emotional or psychological stress. Therefore, get urticaria do not worry or worry, keep a healthy attitude, can improve the body resistance. Usually pay attention to mental health, avoid adverse stimulation. People with a history of urticaria should pay attention to keeping indoor and outdoor cleanliness, and keep fewer pets such as cats and dogs at home. At the same time, we should pay attention to the change of temperature, increase or decrease clothing with the change of temperature, and strengthen physical exercise.
