What is the cause of coramin poisoning?

summary

Poisoning was caused by excessive dose or continuous injection of large dose of Coramine. Lobelia barbata, pedicel and its seeds all contain pedicel alkaloid, which can also lead to poisoning if taken orally. This drug directly excites the respiratory center of the medulla oblongata and stimulates the chemoreceptor of carotid body to excite the respiratory center reflexively.

What is the cause of coramin poisoning?

Poisoning is caused by overdose or multiple injections of this drug. Lobelia chinensis, pedicel and its seeds all contain pedicel alkaloid, which can also lead to poisoning if taken orally. This drug directly excites the respiratory center of the medulla oblongata and stimulates the chemoreceptor of carotid body to excite the respiratory center reflexively. Such drugs inhibit respiration and affect the systemic circulation of the heart. Pulmonary circulation causes abnormalities in the central system.

Common symptoms: nausea and vomiting, headache and dizziness, sweating, cough, rapid breathing, dyspnea, diarrhea, abdominal pain, urethral burning, convulsions. Children with poisoning may have nausea, vomiting, headache, dizziness, paresthesia, sweating, coughing, deep breathing, acceleration, and even dyspnea, tachycardia, arrhythmia, pupil narrowing, slow response to light and even disappear, and see muscle tremor and convulsion, mental disorder, convulsion, coma, blood pressure and hypothermia, etc. Diarrhea, abdominal pain and burning sensation of urethra are often found in the poisoning. Severe poisoning, due to convulsion or respiratory center over excited, followed by inhibition, and eventually respiratory failure.

Examination items: liver function examination, renal function examination, electrocardiogram. An overdose poisoning for a liver and kidney function examination on the line, poisoning patients for a long time, should regularly check ECG. Dry and wet rales can be heard in the lungs. X-ray showed patchy shadows in both lungs. It can be recovered after two weeks. Occasionally, liver and kidney failure occurred. In a few cases, pulmonary fibrosis may occur and pulmonary ventilation dysfunction may be left. Check the blood routine, urine routine, liver and kidney function.

matters needing attention

The key to prevention is not to abuse this kind of drugs, and to educate children not to eat lobelia, pedicel and its seeds. Develop good hygiene habits. Wash your hands before and after meals. Bad personal hygiene habits will bring pathogens from the human body to food. If the hands are contaminated with pathogenic bacteria, and then go to get the food, the contaminated food will enter the digestive tract. Be careful not to eat food containing Coramine.