What problem is serum uric acid high

summary

On Sunday, my uncle came to our house and talked about the recent physical examination organized by his unit. The results showed that the serum uric acid was high, so he consulted the doctor. Let's talk about the problem of high serum uric acid.

What problem is serum uric acid high

First: excessive intake of purine: the high level of blood uric acid is directly proportional to the purine content in food. 50% of RNA and 25% of DNA in food should be excreted in urine as uric acid, which is one of the reasons for high blood uric acid. Strict restriction of purine intake can reduce the serum uric acid content to 60umol / L (1. The level of uric acid in urine decreased to 1. 2mmol/d(200mg/d)。

Second, the high level of serum uric acid is due to the excessive production of endogenous purine. Endogenous purine metabolic disorder is more important than exogenous factors. The de novo synthesis of purine from noncyclic to cyclic goes through 11 steps, in which the abnormal number of enzymes will lead to excessive purine synthesis.

Third: high blood uric acid is also caused by other diseases: such as long-term fasting and diabetes, which often causes the increase of ketone body in blood and excretion from urine, competitively inhibits the excretion of uric acid in blood by renal tubules, so it can increase the concentration of uric acid in blood. Generally speaking, gout may be considered when uric acid exceeds the normal value. This is a metabolic disease, if not controlled, it will lead to problems in all systems of the body.

matters needing attention

High serum uric acid will make the patient's body appear a lot of abnormal reactions. Here we also suggest that you should pay attention to the daily physical examination at ordinary times, and regular physical examination will let you know which part of your body has more problems and needs attention.