What's the matter with carbon tetrachloride poisoning?
summary
Poisoning incidents often happen around us, and carbon tetrachloride poisoning is also one of the common, carbon tetrachloride can cause serious damage to the human body, so in order to avoid poisoning, we should also know the treatment methods after carbon tetrachloride poisoning, and timely rescue. What's the matter with carbon tetrachloride poisoning? Now let me tell you something.
What's the matter with carbon tetrachloride poisoning?
CCl4 and its decomposition products can be absorbed through respiratory tract and skin. It metabolizes rapidly in the body. After inhalation, about 50% of it is excreted from the lung in its original form, and 20% of it is oxidized and transformed in the body. The final product is carbon dioxide. CCl4 can anaesthetize the central nervous system and damage the peripheral nerves, but the liver damage is more prominent.
CCl4 can produce free radical-c · CL3 by hydroxylase in the endoplasmic reticulum of hepatocytes, which leads to lipid peroxidation, endoplasmic reticulum changes, lysosome rupture, mitochondria damage and calcium ion permeability changes, resulting in hepatocyte necrosis. This is a possible cause of liver damage. In addition, CCl4 can also cause degeneration and necrosis of renal tubular epithelial cells, leading to renal damage.
Patients with organic diseases of liver, kidney, heart or nervous system are not allowed to work with carbon tetrachloride. Workers should not drink alcohol. When entering the working environment with high concentration of carbon tetrachloride, you must wear a filter type or oxygen supply type mask. When using carbon tetrachloride fire extinguisher, you should wear gas mask and pay attention to the risk of phosgene poisoning. It is forbidden to wash hands or work clothes with carbon tetrachloride. Do a good job of employment health examination and regular health examination.
matters needing attention
The production process of carbon tetrachloride should be strictly closed. The process of using carbon tetrachloride should be fully ventilated. When entering the high concentration carbon tetrachloride working environment, you must wear a filter or oxygen supply mask. When using carbon tetrachloride fire extinguisher, you should wear a gas mask. Pay attention to the danger of gas in phosgene, popularize prevention knowledge, and publicize that contacts should not drink alcohol, It is forbidden to wash hands or work clothes with carbon tetrachloride. In addition, it is necessary to do a good job in employment health examination and regular health examination. Patients with liver, kidney and organic nervous system diseases should not be exposed to carbon tetrachloride.