Symptoms of steroid dependent dermatitis

summary

For hormone dependent dermatitis, many people are not very clear about it, but in fact, the existence of this disease has a great impact on many patients. Moreover, the incidence rate of this disease has gradually increased in recent years, and its disease is difficult to cure, which has caused great distress to many patients and their families. Next, let's specifically understand the symptoms of hormone dependent dermatitis.

Symptoms of steroid dependent dermatitis

Local long-term external use of hormones, hormones by interfering with the differentiation of the epidermis, induce changes in skin structure and function, inhibit the proliferation of keratinocytes. It results in the decrease of the formation of clear cuticle granules and the thinning of cuticle. The thinning of dermis is due to the change of viscoelasticity of glycoprotein and proteoglycan, which weakens the adhesion between collagen fibrils and reduces the synthesis of collagen.

Due to the decrease in the number of layers of the stratum corneum, the melanin migrating to the keratinocytes decreases, causing hypopigmentation. Pigmentation may be related to glucocorticoid activating melanocyte to regenerate pigment.

In hormone induced rosacea like lesions, the density of Demodex follicularis increased significantly. Demodex follicularis blocked the outlet of sebaceous glands of hair follicles, acted as a carrier of bacteria, causing inflammation or allergy. Powerful hormone can also make sebaceous glands proliferate, leading to a unique rosacea like rash. Hormone can make hair follicle epithelial degeneration, leading to outlet blocked, acne like rash or make the original acne worse.

matters needing attention

In the treatment of hormonal dermatitis, we should not use some medical skin care products with moisturizing, soothing and anti-inflammatory effects of spices and sensitizing preservatives to repair the barrier function of the skin.