Oral leukoplakia is syphilis symptoms?

summary

Syphilis is a chronic sexually transmitted disease caused by Treponema pallidum. Human is the only source of infection of syphilis. Acquired syphilis is mainly transmitted through sexual contact. Treponema pallidum into the human body after about 1 week to 2 months after the incubation period of syphilis symptoms, mainly for hard chancre, hard chancre can be cured without treatment. After chancre subsided, it entered secondary syphilis about 3-4 weeks. The course of secondary syphilis is usually within 2 years. Two patients diagnosed as secondary syphilis by laboratory examination were reported as follows. Let's share the following oral leukoplakia is syphilis symptoms?.

Oral leukoplakia is syphilis symptoms?

First: from September 2015 to February 2016, 2 patients with oral mucosal lesions in our department were selected as the research objects, and they were diagnosed as secondary syphilis by laboratory examination. Patient 1: male, 40 years old, divorced, self-employed. Three months ago, the patient first visited the oral and maxillofacial surgery department for the discovery of gray plaque with ulceration and erosion in the right buccal mucosa near the corner of the mouth. The pathological diagnosis was as follows: white plaque with ulceration and infection.

Second: the incision in the operation area recovered well and the mucosa returned to normal. One week ago, due to the recurrence of gray plaque in the right buccal mucosa near the corner of the mouth and the appearance of new gray lesions on the palate, the patient was referred to our department. There was no obvious fever, headache, dizziness and other symptoms before the onset of the disease. Careful inquiry of the disease history showed that the patient had multiple history of dirty sexual intercourse within one year. Examination: there were irregular gray white patches on the mucosa of the right corner of the mouth, slightly higher than the surrounding mucosa, with bright surface, clear boundary and shallow ulcer (Fig. 1). There were irregular gray white patches on the upper palate, with bright protuberance, clear boundary and red halo around (Fig. 2). No obvious abnormality was found in the skin and genital organs of the limbs and trunk.

Third: laboratory examination: blood routine, liver and kidney function were normal, TP AB (+), RPR 1:64 (+), HIV screening: (-). Diagnosis: mucosal plaque of secondary syphilis.

matters needing attention

Diagnosis: mucosal plaque of secondary syphilis. Treatment and follow-up: benzathine penicillin 2.4 million U was injected into bilateral buttocks muscle once a week for 3 times. After 6 months follow-up, RPR titer decreased to 1:2 (+) and follow-up was continued.