What causes uremia

summary

Most of the patients with uremia are male, and most of the time they find uremia is late, so they have to have a physical examination every year to share with you the causes of uremia.

What causes uremia

Reason 1: the accumulation of urea in the digestive system into the digestive tract, in the intestine by the role of bacterial urease to form ammonia, can stimulate gastrointestinal mucosa, cause cellulosic inflammation, serious is will lead to gastric ulcer and gastric bleeding. There are many places that can get sick, from the mouth, esophagus to rectum. Uremic esophagitis, gastritis and colitis are common. Patients often have nausea, vomiting, abdominal pain, diarrhea, hematochezia and other manifestations.

Reason two: heart and lung disease, sodium retention, renal ischemia, increased renin secretion caused by hypertension can cause heart failure for a long time. * High blood urea infiltration into pericardium and pleura can cause cellulosic pericarditis and cellulosic pleurisy, and the friction sound of pericardium and pleura can be heard during auscultation. Heart failure can cause pulmonary edema. The excretion of blood urea from the respiratory tract can cause respiratory tract inflammation, sometimes along the alveolar wall can have transparent membrane formation; pulmonary capillary permeability increases, there are a lot of fibrin and monocyte exudation in the alveolar cavity, few neutrophils, known as uremic pneumonia.

Reason 3: the main changes of hematopoietic system are anemia and hemorrhage. Causes of anemia: ① insufficient production of erythropoietin in severe renal tissue damage. ② Some metabolites accumulated in the body, such as phenols and their derivatives, can inhibit the hematopoietic function of bone marrow. Other poisons such as guanidine and its derivatives can shorten the survival time of red blood cells, accelerate the destruction of red blood cells and cause hemolysis. ③ Transferrin is lost too much from urine, resulting in the transport of iron in the body.

matters needing attention

People with uremia should drink more water and eat more fresh fruits and vegetables in their life. Don't lose hope of life because of uremia. Now the medical level is very developed, and the treatment of uremia is still very good. We should keep an optimistic attitude towards life.