Symptoms of ciliary immobility syndrome

Update Date: 2025-11-20 Source: Network

summary

Immobile cilia syndrome is a multiple inherited disease caused by ciliary defects. Autosomal recessive inheritance, including abnormal syndrome and other monogenic diseases, incidence rate is about 1: 30000~1: 60000. ICs is a genetic defect of ciliary structure. The main reason is the defect of ciliary protein arm or radiation, which leads to abnormal ciliary movement and dysfunction of ciliary clearance on mucosa, resulting in repeated infection. Sperm tail is a special cilia. When its structure is abnormal, the sperm loses its motility, resulting in infertility. During embryonic development, if the cilia structure is abnormal, due to the lack of normal cilia swing, visceral rotation will occur randomly; On the 10th to 15th day of pregnancy, the left rotation of viscera will replace the right rotation, which will lead to visceral transposition. Let's talk about the symptoms of ciliary immobility syndrome

Symptoms of ciliary immobility syndrome

Early onset, often in the early neonatal or infant onset, airway obstruction, dyspnea. Due to the defect of ciliary structure and dysfunction of clearance,

Recurrent upper respiratory tract infection, chronic bronchitis or interstitial pneumonia, leading to atelectasis and bronchiectasis. The symptoms included cough, expectoration, hemoptysis and dyspnea.

* chronic rhinitis and sinusitis cause retention of mucus or purulent secretion in the sinuses, and pus in the nostrils. There may also be nasal polyps, frontal sinus abnormalities or other nasal sinus hypoplasia. Abnormal cilia of middle ear and eustachian tube can cause chronic recurrent otitis media, perforation of tympanic membrane and ear pus. Loss of sperm tail swing ability can lead to infertility. The structure of cilia in embryonic ciliated cells is abnormal, which may cause partial or complete transposition of viscera.

matters needing attention

Suitable diet: 1. It is suitable to eat food rich in zinc; 2. Food rich in calcium should be eaten; 3. Food rich in protein should be eaten.