What's the cause of variable spasm?
summary
Spasm refers to the muscle suddenly uncontrollable for not random contracture, used to be known as cramps, generally will make a sudden pain, resulting in uncoordinated muscle movements. Generally, when the muscle suddenly tense, involuntary twitch, keep shaking, people's will is uncontrollable, should take emergency measures to relieve pain. What's the cause of variable spasm? Next, I'd like to share my views with you.
What's the cause of variable spasm?
The common causes of athetosis are: (1) hereditary or familial: most of them are autosomal recessive inheritance, which is rare; ② Cerebrovascular accident; ③ Intracranial infection; ④ Drugs; ⑤ Cerebral palsy: cerebral palsy caused by various reasons can appear hand foot bradykinesia; ⑥ High cervical spinal cord lesions.
Hereditary or familial chorea is usually autosomal recessive inheritance, which is rare. In Japan, a familial gene is located in 2q31-36, and can be further located between d2s164 and d2s377. This region encodes PDC gene. At present, a new X-linked hereditary disease, located in Xp11, can cause chorea, It was also accompanied by mental retardation and abnormal behavior; Other hereditary neurological diseases, such as leukodystrophy, spinocerebellar ataxia, hepatolenticular degeneration and familial hypoproteinemia, may also be accompanied by hand foot hyperactivity disorder.
Creutzfeldt Jakob disease caused by intracranial infection with lentivirus can lead to dementia, myoclonus and bilateral finger movement. MRI showed atrophy of bilateral caudate nucleus and putamen and high signal intensity on T2WI; Intracranial infection of herpes simplex virus, Mycoplasma pneumoniae, Toxoplasma gondii and AIDS can also cause hand foot hyperactivity disorder.
matters needing attention
The prevention of hand foot hyperactivity disorder with genetic background is more important. The preventive measures include avoiding consanguineous marriage, carrying out genetic counseling, carrier gene testing, prenatal diagnosis and selective abortion to prevent the birth of children.
