What causes diabetes

summary

With the improvement of living standards, especially now, the pressure of life on many workers also has a certain impact on their health. Diabetes is a common disease nowadays. According to the survey, the incidence rate of this disease is very high in China. Many patients have only recently thought of curing the disease quickly after having this disease. What causes diabetes? Let me talk about it.

What causes diabetes

First: genetic factors: diabetes has familial genetic susceptibility. However, the heredity still needs the effect of external factors, which mainly include obesity, reduced physical activity, unreasonable diet structure, virus infection and so on.

Second: obesity: obesity is an important cause of diabetes. Especially easy to cause type 2 diabetes. Especially abdominal obesity. The main mechanism is that obese people have obvious hyperinsulinemia. Hyperinsulinemia can reduce the affinity between insulin and its receptor, resulting in the inhibition of insulin action and insulin resistance.

Third: oxidative stress: more and more basic and clinical studies show that oxidative stress is closely related to the pathological changes of diabetes. Under the condition of hyperglycemia, due to the hypermetabolism of polyols, the self oxidation of glucose, oxidative phosphorylation and so on, the excessive production of reactive oxygen species free radicals, non enzymatic glycation reaction reduces the antioxidant capacity of SOD and so on, leading to oxidative stress state, damaging biological macromolecules, changing the intracellular information transmission, damaging the structure and function of cells.

matters needing attention

Usually to avoid excessive fatigue, more to ensure adequate sleep. Keep a good mood and avoid being too nervous and depressed. But also to strengthen physical exercise, enhance the body's resistance.