Is medulloblastoma related to genes

summary

Neighbor's child got medulloblastoma disease, there will be nausea and headache, then, medulloblastoma and gene relationship? Now through the etiology of the disease and everyone to introduce.

Is medulloblastoma related to genes

In the field of Neurosurgery, some tumors have obvious familial tendency, such as retinoblastoma, angioreticuloma, multiple neurofibroma and so on. Generally speaking, they are autosomal dominant hereditary tumors with high penetrance. Cell and molecular studies showed that the short arm of chromosome 17 (17p) was lost in 26% - 45% of medulloblastomas. However, although there is a tumor suppressor gene p53 on 17p, further studies show that there is no significant correlation between medulloblastoma and p53 gene mutation or loss, and the changes of oncogenes and tumor suppressor genes related to medulloblastoma are still unclear.

Second, the etiology of the virus theory, experimental studies show that some viruses, including DNA viruses and RNA viruses, can induce brain tumors if inoculated in the animal brain, which is a common etiology, in peacetime also need to pay attention to and actively prevent.

There are many reports about intracranial tumors caused by head radiotherapy. Among the chemical factors, polycyclic aromatic hydrocarbons and nitrates, such as methylcholanthrene, benzo ratio, methylnitrosourea and nitrosopiperidine, can induce brain tumors in some animal experiments.

matters needing attention

Medulloblastoma is a serious disease. When symptoms appear, we should go to the hospital in time. We should take good care of our children, especially to make their life regular.