Why do you have combined immunodeficiency?

summary

My brother's baby got a serious illness when he was three months old. After that, the child's health condition was very bad. The doctor diagnosed it as combined immunodeficiency syndrome, so why did he get combined immunodeficiency? Let me tell you.

Why do you have combined immunodeficiency?

The first reason is that some of the causes of combined immunodeficiency are caused by congenital teratogenic factors, such as bone marrow pluripotent hematopoietic stem cell dysplasia; some are caused by autosomal or sex chromosome recessive inheritance, such as SCID, Wiskott Aldrich syndrome, etc. These patients showed both cellular and humoral immune deficiency.

The second reason is severe combined immunodeficiency disease, including autosomal recessive SCID, ADA deficiency SCID, X-linked recessive SCID, and leucopenia SCID. The immunodeficiency with thrombocytopenia and eczema is X-linked recessive inheritance, and the basic deficiency is unknown. Once the disease occurs, it is best to check and treat in time.

Third, ataxia telangiectasia is autosomal recessive. Cellular immunodeficiency with abnormal immunoglobulin synthesis is characterized by decreased lymphocytes and lymphoid tissue, abnormal pleura structure, different levels of various immune proteins in serum, some increased or decreased, some normal.

matters needing attention

After the emergence of immunodeficiency syndrome, we should strengthen nursing and nutrition to improve the patient's resistance and immunity. Attention should be paid to isolation to minimize contact with pathogens. For severe combined immunodeficiency disease, children must be placed in sterile warehouse for a long time until the immune function is reconstructed. Avoid vaccination: Live vaccinations such as vaccinia and BCG should be prohibited for newborns with suspected immune deficiency, so as to avoid the occurrence of systemic vaccinia due to vaccinia and death due to systemic dissemination caused by BCG vaccination.