Is myasthenia gravis hereditary

summary

I am a patient with myasthenia gravis. The muscle strength of ilium is normal and it is difficult to swallow. Now my symptoms are getting worse year by year. After treatment, I have basically recovered. Now I would like to share with you the genetic problems of myasthenia gravis.

Is myasthenia gravis hereditary

First: myasthenia gravis is a pleomorphic autoimmune disease. More than 4% of the patients had family history, and the genetic consistency of monozygotic twins was 36%. Some familial myasthenia gravis is caused by neuromuscular conduction defect, which is called congenital myasthenia gravis. It belongs to autosomal recessive inheritance. Acetylcholine receptor antibody can not be detected in serum, and most of them occur at birth.

Second, about 9% of myasthenia gravis patients have other autoimmune diseases, such as thyroiditis and rheumatoid arthritis. The higher positive rate of acetylcholine receptor antibody in the first degree family members of the patients also suggested that myasthenia gravis had a certain genetic tendency. Studies have shown that the susceptibility of myasthenia gravis is related to the gene expression of HLA, acetylcholine receptor and T cells, which has the characteristics of complex multi gene control.

Third: there are often some patients with myasthenia gravis in the treatment of disease at the same time, very concerned about whether myasthenia gravis will be passed on to the next generation? The answer is that myasthenia gravis is not infectious, but it is a genetic disease.

matters needing attention

This disease needs attention: general weakness, masticatory weakness, neck myasthenia gravis, facial myasthenia gravis: patients often feel severe general weakness, shoulder can't lift, hand can't lift, squat down to stand up, bite things not strong, patients sit with drooping head phenomenon, with the hand holding chin can hold the head up, the whole facial expression of myasthenia gravis.