What are the symptoms of pulmonary nodules

summary

Pulmonary nodule is a granulomatous disease of multiple systems and organs with unknown etiology. It often invades the lung, bilateral hilar lymph nodes, eyes, skin and other organs. Its chest invasion rate is as high as 80% - 90%.

What are the symptoms of pulmonary nodules

First, sarcoidosis is the result of the interaction between unknown antigens and cellular and humoral immune functions. Due to individual differences (age, gender, race, genetic factors, hormones, HLA) and the regulatory role of antibody immune response, depending on the imbalance between the promoters and antagonists, the development and regression of granuloma are determined, showing different pathological states and natural remission trend of sarcoidosis.

Second, the primary lesion of pulmonary sarcoidosis is alveolitis with extensive infiltration of monocytes, macrophages and lymphocytes, involving the alveolar wall and stroma. Both alveolitis and granuloma may dissipate spontaneously.

Third: but in the chronic stage, the fibroblasts around granuloma are collagenous and glassy, and become non-specific fibrosis. The histopathological features of granuloma are not specific. It can be seen in Mycobacterium and fungi infection, or in foreign body or traumatic tissue reaction. It can also be seen in beryllium disease, third stage syphilis, lymphoma and exogenous allergic alveolitis. It should be differentiated.

matters needing attention

Sarcoidosis is related to the condition of the disease. The prognosis of patients with acute onset is better after treatment or self remission, while the prognosis of patients with chronic progressive pulmonary fibrosis or acute infection is worse. The cause of death is usually pulmonary heart disease or invasion of myocardium and brain.