What symptom does hormone dependence dermatitis have?

summary

Corticosteroid dependent dermatitis (referred to as steroid dependent dermatitis) is caused by long-term repeated inappropriate external use of hormones. In recent years, due to the rising trend of the incidence year by year, and stubborn and difficult to cure, it has become the focus of medical experts. What symptom does hormone dependence dermatitis have? Let's talk about it

What symptom does hormone dependence dermatitis have?

Local long-term external use of hormones, hormones by interfering with the differentiation of the epidermis, induce changes in skin structure and function, inhibit the proliferation of keratinocytes. It results in the decrease of the formation of clear cuticle granules and the thinning of cuticle. The thinning of dermis is due to the change of viscoelasticity of glycoprotein and proteoglycan, which weakens the adhesion between collagen fibrils and reduces the synthesis of collagen.

Due to the decrease in the number of layers of the stratum corneum, the melanin migrating to the keratinocytes decreases, causing hypopigmentation. Pigmentation may be related to glucocorticoid activating melanocyte to regenerate pigment.

In hormone induced rosacea like lesions, the density of Demodex follicularis increased significantly. Demodex follicularis blocked the outlet of sebaceous glands of hair follicles, acted as a carrier of bacteria, causing inflammation or allergy. Powerful hormone can also make sebaceous glands proliferate, leading to a unique rosacea like rash. Hormone can make hair follicle epithelial degeneration, leading to outlet blocked, acne like rash or make the original acne worse.

matters needing attention

There is no special need to pay attention to the food, keep healthy eating habits. Attention should be paid not to take health care products and supplements with unknown origin and composition, so as to avoid excessive hormone levels and aggravating the disease.