Can undifferentiated arthritis worsen?

summary

Undifferentiated arthritis has been known as "undefined arthritis", "serum negative polyarthritis", "undifferentiated serum negative polyarthritis", "HLA-B27 associated arthritis" and so on. People use "early arthritis", "early rheumatoid arthritis (RA)" or "UA" to refer to the patients who may develop RA, and also to refer to the patients who have been diagnosed with RA. Can undifferentiated arthritis worsen? Let's talk about it

Can undifferentiated arthritis worsen?

The majority of UA patients with occult onset, metacarpophalangeal joint, wrist joint and other limb joints swelling, pain, stiffness, some patients may have infection and other inducing factors. It can only have joint swelling and pain symptoms, and can also be accompanied by extraarticular manifestations, such as general discomfort, fatigue, etc.

It can be single joint or multi joint at the same time, mostly small joints of limbs, or large joints such as knee and elbow. The course of disease varies from several weeks to several years, and can progress to RA, systemic lupus erythematosus (SLE), ankylosing spondylitis (as), osteoarthritis, reactive arthritis, etc,

Some patients were followed up for decades and still did not meet the classification criteria of RA in ACR. Some patients had natural remission or had no change in symptoms for many years. In his study, UA was defined as at least one joint swelling or pain with abnormal inflammatory indicators, including increased erythrocyte sedimentation rate (ESR), or C-reactive protein (CRP), increased peripheral white blood cell count, or positive rheumatoid factor (RF). At the same time, the possibility of joint symptoms of crystalline arthritis and other diseases must be excluded.

matters needing attention

First of all, the patients should be aware of the disease. Physical exercise should be carried out step by step to prevent excessive movement and weight bearing of joints and avoid mechanical injury of joints. If it is serious, it should be fixed with brake or plaster to prevent deformity. Reduce weight and use handlebars and canes to reduce the load on the affected joints. Those related to occupation should change jobs. Exercise related muscle groups can maintain and improve joint activity, so as to enhance joint stability.